A 54-year-old Man with History of PTSD

By Violeta O. Tan, MD; Natalie L. Rasgon, PhD

A 54-year-old man with history of depression and posttraumatic stress disorder (PTSD) was re-admitted to the hospital with the chief complaint of malaise. Previous admission 9 days prior was for a urinary tract infection (UTI), which was treated with ciprofloxacin 500 mg bid. During this first admission, his outpatient psychotropic medications (quetiapine 300 mg/day and bupropion 225 mg/day) were restarted without titration. He had self-discontinued these agents 6 to 8 months prior after reportedly feeling well. Patient was discharged on hospital day 4 in stable condition with ciprofloxacin 500 mg bid, quetiapine 300 mg/day, and bupropion 225 mg/day. He was feeling well until 5 days after discharge when he began experiencing fatigue, warmth, chills, and loose stools, for which he was re-admitted to the hospital.